Peptika.
Cat. 06
Type I · Lyophilised
PK-2026-RETATR
Peptika Retatrutide vial
Lot-tracedEU pharmacyCold-chain 2–8 °C
06 · Weight Management

Retatrutide.

Triple GLP-1/GIP/glucagon agonist — under clinical investigation for advanced metabolic protocols.

Select strengthPer-vial price
Quantity
1
Total
€100.00· 1 vial

Build your bag, then either book a consultation (an EU-licensed physician reviews your file — anything declined is refunded) or upload an existing Rx at checkout.

  • Magistral preparation — Directive 2001/83/EC Art. 5(1).
  • Patient-named prescription only — dispensed against a valid Rx.
  • EU-GMP Annex 1 Grade A/B cleanroom compounding.
  • Cold-chain shipping across EU/EEA — 2–5 working days.
Overview

About Retatrutide.

Retatrutide is a triple agonist of the GLP-1, GIP and glucagon receptors. Phase 2 data published in 2023 showed weight loss exceeding any previously published GLP-1-class result. Phase 3 trials are ongoing.

Retatrutide does not yet hold a Marketing Authorisation. Magistral compounding requires individual physician judgement — the evidence base is more recent and the safety database smaller than for Semaglutide or Tirzepatide.

Mechanism of action

Triple agonism. GLP-1 receptor activation drives appetite suppression and glycemic control; GIP receptor activation modulates β-cell function and adipose handling; glucagon receptor activation increases energy expenditure via thermogenic and hepatic lipolysis pathways. The combination drives weight loss faster than dual-agonist molecules.

Posology · for information only

Subcutaneous injection, once weekly. Slow titration over several months from a low starting dose (1–2 mg) to a maintenance dose typically in the 4–12 mg range, depending on tolerance and clinical response.

Your physician sets the prescription. This is descriptive information, not a self-administration guide.

Storage

Lyophilised: store at 2–8 °C, protect from light. Once reconstituted: 2–8 °C, use within 30 days. Do not freeze.

Evidence baseClinical RCT evidence
Indications studied
Obesity (investigational)Type 2 diabetes (investigational)
Selected references
  1. 01Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity. N Engl J Med · 2023 · doi: 10.1056/NEJMoa2301972
Identification & specifications
INN / Name
Retatrutide
Form
Lyophilised vial · subcutaneous injection
Strength
5mg vial
Manufacturing
EU-GMP Annex 1 · Grade A/B
Endotoxins
European Pharmacopoeia 2.6.14 · LAL assay
Identity & purity
HPLC + MS · > 98%
Cold chain
Validated 2–8 °C, monitored end-to-end
Regulatory basis
Directive 2001/83/EC · Article 5(1)
Logistics

2–5 working days

EU / EEA cold-chain delivery, 2–8 °C monitored end-to-end with digital temperature log. Tracking link sent on dispatch.

Legal status

Magistral preparation

Patient-named preparation under Directive 2001/83/EC Article 5(1). Dispensed exclusively against a valid EU prescription.

Cross-border

EU prescription recognition

Prescriptions written in one EU member state are recognised in others under Directive 2011/24/EU on cross-border healthcare.