MOTS-c.
Mitochondrial-derived peptide — AMPK activation, glucose homeostasis, exercise mimetic.
Build your bag, then either book a consultation (an EU-licensed physician reviews your file — anything declined is refunded) or upload an existing Rx at checkout.
- ✓Magistral preparation — Directive 2001/83/EC Art. 5(1).
- ✓Patient-named prescription only — dispensed against a valid Rx.
- ✓EU-GMP Annex 1 Grade A/B cleanroom compounding.
- ✓Cold-chain shipping across EU/EEA — 2–5 working days.
About MOTS-c.
MOTS-c (Mitochondrial Open Reading frame of the Twelve S rRNA-c) is a 16-amino-acid peptide encoded in the mitochondrial genome itself. Discovered in 2015, it acts as a metabolic regulator and is sometimes described as an 'exercise mimetic'.
Plasma MOTS-c declines with age and is reduced in insulin-resistant patients. Pre-clinical models show striking effects on metabolic health and physical performance.
MOTS-c activates AMPK in skeletal muscle and adipose tissue, mimicking many of the cellular consequences of exercise. It improves insulin sensitivity via the folate-cycle / AICAR-AMPK axis and modulates expression of nuclear genes involved in metabolic stress.
Subcutaneous injection, typically 5–10 mg per dose, 2–3 times per week.
Your physician sets the prescription. This is descriptive information, not a self-administration guide.
Lyophilised: store at 2–8 °C, protect from light. Once reconstituted: 2–8 °C, use within 30 days. Do not freeze.
- 01Lee C, et al. — The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis. Cell Metab · 2015 · doi: 10.1016/j.cmet.2015.02.009
- INN / Name
- MOTS-c
- Form
- Lyophilised vial · subcutaneous injection
- Strength
- 5mg vial
- Manufacturing
- EU-GMP Annex 1 · Grade A/B
- Endotoxins
- European Pharmacopoeia 2.6.14 · LAL assay
- Identity & purity
- HPLC + MS · > 98%
- Cold chain
- Validated 2–8 °C, monitored end-to-end
- Regulatory basis
- Directive 2001/83/EC · Article 5(1)
2–5 working days
EU / EEA cold-chain delivery, 2–8 °C monitored end-to-end with digital temperature log. Tracking link sent on dispatch.
Magistral preparation
Patient-named preparation under Directive 2001/83/EC Article 5(1). Dispensed exclusively against a valid EU prescription.
EU prescription recognition
Prescriptions written in one EU member state are recognised in others under Directive 2011/24/EU on cross-border healthcare.