
Spermidine (injectable).
Polyamine — autophagy inducer studied for cardiovascular and cognitive ageing.
Build your bag, then either book a consultation (an EU-licensed physician reviews your file — anything declined is refunded) or upload an existing Rx at checkout.
- ✓Magistral preparation — Directive 2001/83/EC Art. 5(1).
- ✓Patient-named prescription only — dispensed against a valid Rx.
- ✓EU-GMP Annex 1 Grade A/B cleanroom compounding.
- ✓Cold-chain shipping across EU/EEA — 2–5 working days.
About Spermidine (injectable).
Spermidine is a naturally occurring polyamine present in many foods and synthesised in the body. It is one of the most studied non-pharmacological autophagy inducers, with epidemiological and animal data linking higher intake to extended lifespan.
An injectable form bypasses gut metabolism and delivers a precise dose. Human RCT data is accumulating, particularly in cognitive ageing.
Spermidine inhibits histone acetyltransferases (HAT), shifting the histone-acetylation balance and inducing autophagy via ATG transcription. This results in clearance of damaged organelles and proteins — particularly relevant in cardiomyocytes and neurons.
Subcutaneous injection, typically 10–20 mg per dose, 2–3 times per week.
Your physician sets the prescription. This is descriptive information, not a self-administration guide.
Lyophilised: store at 2–8 °C, protect from light. Once reconstituted: 2–8 °C, use within 30 days. Do not freeze.
- INN / Name
- Spermidine (injectable)
- Form
- Lyophilised vial · subcutaneous injection
- Strength
- 20mg vial (injectable)
- Manufacturing
- EU-GMP Annex 1 · Grade A/B
- Endotoxins
- European Pharmacopoeia 2.6.14 · LAL assay
- Identity & purity
- HPLC + MS · > 98%
- Cold chain
- Validated 2–8 °C, monitored end-to-end
- Regulatory basis
- Directive 2001/83/EC · Article 5(1)
2–5 working days
EU / EEA cold-chain delivery, 2–8 °C monitored end-to-end with digital temperature log. Tracking link sent on dispatch.
Magistral preparation
Patient-named preparation under Directive 2001/83/EC Article 5(1). Dispensed exclusively against a valid EU prescription.
EU prescription recognition
Prescriptions written in one EU member state are recognised in others under Directive 2011/24/EU on cross-border healthcare.